Ayahuasca Cusco Retreat
We run ayahuasca retreats in Cusco, in Peru’s Sacred Valley, guided by Shipibo and Q’eros healers with 13 year experience. Each retreat combines traditional ceremony with a screening process, a support team present throughout the night, and structured integration afterward — because the medicine does the work, but the container around it is what makes that work safe.
If you’re here because you’re weighing whether to do this in Cusco specifically, that’s worth answering directly: Cusco sits at the meeting point of Amazonian plant medicine and Andean ceremonial tradition. You get the icaros and the Amazonian preparation rituals, but you also get the mountains, the altitude, and a slower pace that a lot of returning guests say changes how the integration lands afterward.
Our Ayahuasca
Retreats in
Cusco
We keep the format simple: pick the length that fits your time and your intention, not the other way around.
Ayahuasca Ceremony in Peru
At Ayahuasca Cusco, we have built retreats to optimize the variables of needs and experience. Our programs offer options for a first approach by way of a short ceremony or possible a more intense immersion over a multiple night stay. Our retreats offer you a safe space to initiate and experience a transformative journey into greater self awareness and consciousness.
Each retreat is advocated by a ceremony leader with a team to offer support throughout your experience, carefully monitoring you for safety, security, and respect so you are never left alone – we are always with you.
One ceremony, one night, guided by an experienced shaman. This is the right entry point if you’re short on time but still want the real thing — not a shortened or “tourist” version, just a single, complete ceremony instead of several.
Two ceremonies with a full day between them for rest and reflection. Most people who choose this over the 1-day option are looking for a second pass at whatever the first ceremony surfaced.
Three nights, with preparation and integration built around each one. This is where a lot of guests start noticing patterns across ceremonies rather than treating each night as separate.
Multiple ceremonies with integration circles between them. Five days gives enough room for the early nights to open something and the later ones to actually work with it, rather than just repeating the experience.
Our longest and most complete program: multiple ceremonies, Andean ritual work, and daily integration sessions. If you’re dealing with something specific — grief, a long-standing pattern, a decision you’ve been circling for years — this is usually the format built for it.
San Pedro (Wachuma) Ceremony in Cusco, Peru: Experience the Sacred San Pedro Medicine in the Andes
San Pedro Ceremony Cusco: A Sacred Andean Healing Tradition
Ayahuasca isn’t the only sacred medicine we work with. San Pedro, known in Quechua as Wachuma, is a daytime ceremony using a cactus medicine that Andean healers have worked with for thousands of years. Where ayahuasca tends to be introspective and nocturnal, Wachuma opens outward — toward nature, toward the mountains around you, toward a gentler and more gradual shift in perception.
Some guests do one or the other. Many combine both across a longer retreat, since they work differently and complement each other rather than compete.
Our 1-Day San Pedro Ceremony is a meaningful introduction to the sacred medicine of Wachuma, offering a gentle yet profound experience of self-discovery, emotional balance, and spiritual connection. Surrounded by the breathtaking landscapes of the Andes and guided by experienced local shamans, you’ll spend the day reconnecting with nature, gaining clarity, and embracing the peaceful energy that has made San Pedro ceremonies a cherished tradition in Peru for centuries.
Why Do This in Cusco
Cusco was the capital of the Inca empire, and that history isn’t incidental to the ceremony — it’s part of why people choose this specific location over the jungle centers near Iquitos or Pucallpa. Three things make Cusco distinct:
The setting itself. The Sacred Valley sits outside the noise of the city, surrounded by the Apus (sacred mountains) and rivers that Andean cosmology has treated as living presences for centuries. You’re not disconnecting from a resort; you’re stepping into a landscape that the tradition itself considers part of the ceremony.
Two traditions in one place. Ayahuasca originates in the Amazon. Cusco is Andean. What happens here is a genuine overlap — Amazonian plant medicine held within Andean ceremonial structure, including offerings to Pachamama and the mountain spirits alongside the icaros sung during the ceremony itself. That combination isn’t available in a purely jungle-based retreat.
Practical accessibility. Cusco has an international airport, a full medical infrastructure if something needs attention beyond what we handle on-site, and enough retreat centers that you can actually compare options before committing — which you should do, regardless of who you end up choosing.
Why Choose Ayahuasca Retreats in Cusco?
Choosing an Ayahuasca retreat in Cusco allows participants to connect with the wisdom of traditional plant medicine while immersing themselves in one of the most energetically significant places in South America. The combination of Andean spirituality, peaceful natural surroundings, and experienced shamans makes Cusco an ideal setting for ceremonies that focus on personal growth, emotional healing, and spiritual exploration.
Another important advantage of participating in Ayahuasca ceremonies in Cusco is the accessibility and diversity of retreat options. Many retreats are located in the Sacred Valley, a tranquil area just outside the city where participants can disconnect from daily stress and fully focus on their spiritual journey. These retreats often provide comfortable accommodations, integration support, and guidance throughout the entire process.
What to Expect from an
Ayahuasca Ceremony in Cusco
No two ceremonies unfold the same way, but the structure around them is consistent. Here’s what the process actually looks like, start to finish.

Preparation & Safety
Before the ceremony, you'll go through a written medical and psychological screening. This isn't a formality — certain medications (particularly SSRIs and MAOIs) and certain conditions make ayahuasca genuinely dangerous, not just inadvisable, and we need accurate information to tell you honestly whether this is right for you. You'll also be asked to follow a short dietary preparation beforehand: no alcohol, no pork, no heavily processed food, for a period leading up to the ceremony.

Guidance and Integration
The ceremonies are led by Shipibo and Queiro shamans, who possess extensive knowledge and a long lineage of ancestral healers. The morning after each ceremony includes a grounding and sharing session. This part matters as much as the ceremony itself — what surfaces during an ayahuasca journey needs somewhere to go afterward, and integration is where that happens.

Physical & Spiritual Benefits
A bunch of folks say their time there totally flipped their world upside down physically, ayahuasca can help cleanse the body and let go of built-up stress on a deep, soulful level, it clears up confusion, heals old hurts, and makes you feel more connected to yourself and the cosmos. Every trip's different, but usually, folks come back feeling lighter, rejuvenated, and fired up to live with more meaning.

During the Ceremony
The ceremony itself takes place at night, led by Shipibo and Quero´s Shamans. Expect an opening explanation of what's about to happen, an intention-setting period, and then the ceremony proper — icaros (traditional healing songs), a dimly lit or dark room, and a support team present the entire time. Physical purging (vomiting) is common and is treated as part of the process, not a complication. You are not left alone at any point.

What People Commonly Report
Reported effects vary a lot by person, and we're careful not to promise outcomes. That said, participants commonly describe emotional release, a period of intense introspection, and — in the weeks following — a clearer sense of what they'd been avoiding or postponing. Ayahuasca doesn't hand you answers; it tends to surface exactly what you'd been not looking at.
Who These Retreats Are For
Our retreats work well for:
- First-time participants who want real guidance rather than being left to figure it out
- Experienced participants looking for deeper or longer work
- Travelers combining ceremony with time in the Sacred Valley or a Machu Picchu trip
- Anyone approaching this as part of an ongoing process, not a one-time fix
They’re not appropriate for people currently on psychiatric medication, anyone with a serious cardiac or psychiatric history, or during pregnancy. We’ll tell you directly if your medical screening rules this out — that conversation happens before you travel, not after you arrive.
The Power of Ayahuasca in Cusco
Spiritual and Emotional Healing
In Cusco, Ayahuasca isnot only a ceremony,but also is a sacred path restoring contact and to your soul.Headed by experienced shamans, this ancient medicine bringsa profound emotional purge that cleanses those barriers and ancient traumas away.A great many of those who go through this experience say that it feels like being born again. The heart and spirit are re-rooted in their natural state.
Connection with Nature and Ancient Traditions
Cusco Mountain guides bless their Ayahuasca clients with the presence of Pachamama (Mother Earth) and Apus cornice (sacred mountain spirits). Combining Amazonian knowledge with Andean spirituality, this set of rituals makes a bridge between two old worlds. This unique consonance helps create some sense of surroundedness for seekers, not only in themselves but in every vein-every fiber; soil and sky.
Why Cusco is the Best Place for Ayahuasca in Peru
The heart of the Andes, Cusco was the ancient capital of the Inca Empire. In a place where history, nature and spirituality come together, Ayahuasca now happens here The sacred valleys, high mountains, and powerful energy of this land make Cusco one of the most authentic and transformational destinations for Ayahuasca in Peru.
Ayahuasca Safety & Preparation Guidelines
- Follow a special diet (dieta) at least 3–7 days before the ceremony (avoid alcohol, pork, drugs, and processed foods).
- Share your medical history openly with the shaman to ensure your safety.
- Approach the medicine with respect, humility, and clear intentions.
- Integration after the ceremony is essential – journaling, meditation, or therapy can help.
Who Are Our Ayahuasca Ceremonies For?
Our ayahuasca retreats in Cusco are ideal for:
- First-time participants seeking proper guidance
- Experienced seekers wanting deeper work
- Travelers looking for an authentic ayahuasca experience in Peru
- Individuals committed to personal and spiritual growth
❌ Not recommended for individuals on psychiatric medication, with severe mental health conditions, or during pregnancy.
Real Experiences & Integration
Integration is just as crucial as the ceremony itself. We advise you on how to apply ideas to everyday living and ground them.
Many people claim that their experience changed their life, not just because of hallucinations but also because of the insight and clarity obtained afterward.
Ayahuasca Benefits: A Personal Journey
While experiences vary, many participants report:
- Emotional release and clarity
- Deep self-awareness
- Spiritual insight and connection
- A renewed sense of purpose
- Healing at emotional and energetic levels
Ayahuasca does not offer quick answers—it reveals what needs to be seen and integrated with care.
What Our Guests Say About Their Ayahuasca Retreat in Cusco
Every ceremony leaves its own mark. These are the words of those who crossed that threshold in the Sacred Valley and chose to share their journey with us.
EXCELLENT Based on 35 reviews Posted on Tripadvisor Antonela PerezVerified Autenticidad Shipiba y cuidado total. Mi ceremonia de ayahuasca el día de hoy fue sencillamente espectacular. Decido dejar este comentario porque me sorprende y me indigna ver reseñas negativas que claramente buscan dañar la reputación de este centro por pura envidia. Mi experiencia fue todo lo contrario: hermosa e inolvidable. El servicio es impecable desde que entras a la oficina; la atención es de primera. El lugar es un oasis de tranquilidad y sentí mucha conexión, el templo tiene una vista increíble y una energía maravillosa. Trabajan con chamanes Shipibos reales, y el maestro Amaru y la maestra Joana estuvieron pendientes de mí durante toda la ceremonia, brindándome una seguridad y una atención extraordinarias. Me siento feliz, en paz y muy agradecida. Lo recomiendo totalmente y regresaré sin dudarlo a mi siguiente ceremonia aquí. ¡Un lugar 10 de 10!Posted on Tripadvisor JULIETA LVerified The best retreat ever! Our experience at the retreat was wonderful. Amaru is responsable, a good person, a good listener, and a good advisor. He took great care to ensure that our entire experience was perfect and that we truly enjoyed it. My husband and I are very greatful and will never forget this experience.Posted on Tripadvisor Tony NVerified Connecting with the higher spirits up in the forests of Cusco I had a life-changing experience with Ayahuasca. I found some answers about the universe and myself which allow me to tackle my next chapter in life with full force and purpose. I can wholeheartedly recommend this retreat. I participated in a two day Ayahuasca retreat organised by Joanna and Amaru. They were very hospitable in organising transport and accommodation in the retreat centre. They eased me into the process before the ceremony so I felt completely ready to receive wisdom from Madre Terra and the Cosmos. The Shaman conducting the ceremonies is experienced, wise and hails from the Peruvian jungle. The volcanic water is essential to cleanse the body of any impurities from the body.Posted on Tripadvisor GrandTour30328834742Verified Experiencia Ayaguasca ⭐️⭐️⭐️⭐️⭐️ Tuve una experiencia espiritual increíble con la medicina natural Ayahuasca, y no puedo dejar de agradecer a Amaru y Johana por su profesionalismo y amor en cada momento. Desde el inicio de las ceremonias, me hicieron sentir en un ambiente seguro y sagrado, lo que permitió que mi viaje interior fuera profundo y transformador. La ceremonia de ofrenda a Pacha Mama fue una experiencia única y renaciente, donde pude conectar con la naturaleza y con mi ser interior de una manera que nunca había experimentado antes. La guía de Amaru y Johana fue invaluable, y su dedicación a la sanación se sintió en cada paso del proceso. Recomiendo encarecidamente esta experiencia a quienes buscan un viaje espiritual auténtico y significativo. ¡Gracias, Amaru y Johana, por todo lo que hicieron por mí! 🌿✨Posted on Tripadvisor Dulce Esperanza AVerified Powerful experience Highly recommended. I had a negative energy cleansing, coca leaf reading and Ayahuasca ceremony. All ceremonies were very emotional and you could tell the personnel were experienced. I was very nervous about taking Ayahuasca but Johanna and the shaman Channan put me at ease, it was very powerful experience indeed and but I was guided through the more difficult bits with care and professionalism. They also help me interpret what I saw.Posted on Tripadvisor Lena SVerified Lifechanging What an experince. A bit chaotic in the beginning, but all in all it was such a beautiful experince! Gonna come back for sure. Thanks for this lifechangin experience.Posted on Tripadvisor Asama QVerified Very cool experience Going here for the first time, initially I was a bit nervous about the experience, but Maestro Channan took us through an amazing ceremony and made us feel very comfortable. Really nice facility too, and it was exciting to see the new one under construction as well.Verified by TrustindexTrustindex verified badge is the Universal Symbol of Trust. Only the greatest companies can get the verified badge who has a review score above 4.5, based on customer reviews over the past 12 months. Read more
Frequently Asked Questions (FAQ) about our Ayahuasca Retreats
What exactly is ayahuasca, and what will I feel during the ceremony?
Ayahuasca is a traditional Amazonian brew made by combining two plants. It isn't a recreational substance — it's a tool used ceremonially for deep psychological and spiritual work. Expect visions, intense emotional introspection, and often physical purging, which is considered part of the cleansing process rather than a side effect. Every experience is different; the facilitators guide and support you throughout.
How many people participate in each ceremony?
We keep groups small 6 persons, so each person gets real attention from the facilitation team rather than being one of a crowd.
Do I need previous experience with psychedelics or spirituality?
No. Most first-time participants have neither. What matters more is your intention and your willingness to be honest during the preparation process.
Is it safe to participate in an ayahuasca ceremony?
It's safe when held in an appropriate ceremonial context, with proper screening and experienced guidance — and it can be genuinely dangerous without either. We conduct a medical evaluation before confirming any booking specifically to rule out contraindications.
Is ayahuasca legal in Peru?
Yes. Peru's government recognized ayahuasca ceremonies as part of the nation's cultural heritage in 2008, and its traditional ceremonial use is legally protected.
What's the difference between ayahuasca and San Pedro (Wachuma)?
Ayahuasca is typically a nighttime, introspective medicine focused on inner work. San Pedro (Wachuma) is a daytime medicine that tends to open awareness outward, toward nature and connection, in a gentler and more gradual way. Some retreats combine both.
What if I have a difficult or overwhelming experience during the ceremony?
That's a normal part of the process, not a sign something's wrong. Facilitators stay present throughout the night specifically to support you through intense moments — you won't be left to navigate it alone.
Can I participate if I'm taking medication, particularly antidepressants?
This is one of the most important questions to answer honestly. SSRIs and MAOIs in particular can interact dangerously with ayahuasca. If you're on any psychiatric medication, talk to your doctor well before your retreat about whether discontinuing it safely is possible — and be completely transparent with us on your medical form regardless.
Ayahuasca
Information
Yes — and thousands of visitors to Cusco do exactly this every year. The combination is logistically natural, geographically coherent, and for many participants, meaningfully coherent too: the Inca heritage
The ceremony ends. The medicine fades. You eat something light, sleep a few hours, and in the morning you feel different — raw and open and somehow larger than you
San Pedro Ceremony: What to Expect — a complete hour-by-hour guide covering the opening rituals, mescaline onset, peak experience, the shaman’s role, and the closing in Cusco’s Sacred Valley. A